CHMP2B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-56956

Novus Biologicals, part of Bio-Techne
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NBP2-56956
NBP2-56956-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CHMP2B Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: TVDDVIKEQNRELRGTQRAIIRDRAALEKQE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CHMP2B Antibody

Immunocytochemistry/ Immunofluorescence: CHMP2B Antibody [NBP2-56956]

Immunocytochemistry/ Immunofluorescence: CHMP2B Antibody [NBP2-56956]

Immunocytochemistry/Immunofluorescence: CHMP2B Antibody [NBP2-56956] - Staining of human cell line U-2 OS shows localization to cytosol.

Applications for CHMP2B Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CHMP2B

Component of the escrt-iii complex, which is required for multivesicular bodies (mvbs) formation and sorting of endosomal cargo proteins into mvbs. the mvb pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. the escrt-iii complex is probably involved in the concentration of mvb cargo. in case of infection, the hiv-1 virus takes advantage of the escrt-iii complex for budding and exocytic cargos of viral proteins.

Long Name

Charged Multivesicular Body Protein 2B

Alternate Names

CHMP2.5, DMT1, Vps2-2, VPS2B

Gene Symbol

CHMP2B

Additional CHMP2B Products

Product Documents for CHMP2B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CHMP2B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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