CHMP4C Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81166

Novus Biologicals, part of Bio-Techne
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NBP1-81166
NBP1-81166-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CHMP4C Antibodies »

Product Summary for CHMP4C Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: MSKLGKFFKGGGSSKSRAAPSPQEALVRLRETEEMLGKKQEYLENRIQREIALAKKHGTQN

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (85%), Rat (84%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CHMP4C Antibody

Immunohistochemistry-Paraffin: CHMP4C Antibody [NBP1-81166]

Immunohistochemistry-Paraffin: CHMP4C Antibody [NBP1-81166]

Immunohistochemistry-Paraffin: CHMP4C Antibody [NBP1-81166] - Staining in human small intestine and testis tissues using anti-CHMP4C antibody. Corresponding CHMP4C RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: CHMP4C Antibody [NBP1-81166]

Immunohistochemistry-Paraffin: CHMP4C Antibody [NBP1-81166]

Immunohistochemistry-Paraffin: CHMP4C Antibody [NBP1-81166] - Staining of human small intestine shows high expression.
Immunohistochemistry-Paraffin: CHMP4C Antibody [NBP1-81166]

Immunohistochemistry-Paraffin: CHMP4C Antibody [NBP1-81166]

Immunohistochemistry-Paraffin: CHMP4C Antibody [NBP1-81166] - Staining of human testis shows low expression as expected.

Applications for CHMP4C Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CHMP4C

CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM]

Alternate Names

charged multivesicular body protein 4c, CHMP4c, chromatin modifying protein 4C, Chromatin-modifying protein 4c, hSnf7-3, hVps32-3, MGC22825, SHAX3, SNF7 homolog associated with Alix 3, Snf7 homologue associated with Alix 3, SNF7-3, Vacuolar protein sorting-associated protein 32-3, Vps32-3, VPS32C

Entrez Gene IDs

92421 (Human)

Gene Symbol

CHMP4C

UniProt

Q96CF2 (Human)

Additional CHMP4C Products

Product Documents for CHMP4C Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CHMP4C Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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