CHMP5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49227

Novus Biologicals, part of Bio-Techne
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NBP2-49227
NBP2-49227-25ul
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CHMP5 Antibodies »

Product Summary for CHMP5 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: KAYKQVKIDQIEDLQDQLEDMMEDANEIQEALSRSYGTPELDEDDLEAELD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CHMP5 Antibody

Western Blot: CHMP5 Antibody [NBP2-49227]

Western Blot: CHMP5 Antibody [NBP2-49227]

Western Blot: CHMP5 Antibody [NBP2-49227] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10
Lane 2: Human Kidney tissue
Immunohistochemistry-Paraffin: CHMP5 Antibody [NBP2-49227]

Immunohistochemistry-Paraffin: CHMP5 Antibody [NBP2-49227]

Immunohistochemistry-Paraffin: CHMP5 Antibody [NBP2-49227] - Staining of human lymph node.
Immunohistochemistry-Paraffin: CHMP5 Antibody [NBP2-49227]

Immunohistochemistry-Paraffin: CHMP5 Antibody [NBP2-49227]

Immunohistochemistry-Paraffin: CHMP5 Antibody [NBP2-49227] - Staining of human kidney shows cytoplasmic positivity in renal tubules.
View 4 more images

Applications for CHMP5 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CHMP5

CHMP5 is a component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. In case of infection, the HIV-1 virus takes advantage of the ESCRT-III complex for budding and exocytic cargoes of viral proteins.

Alternate Names

apoptosis-related protein PNAS-2, C9orf83, charged multivesicular body protein 5, chromatin modifying protein 5, Chromatin-modifying protein 5, chromosome 9 open reading frame 83, HSPC177, hVps60, PNAS-2, SNF7 domain containing 2, SNF7 domain-containing protein 2, SNF7DC2, Vacuolar protein sorting-associated protein 60, Vps60CGI-34

Gene Symbol

CHMP5

Additional CHMP5 Products

Product Documents for CHMP5 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CHMP5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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