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CHMP6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83726

Novus Biologicals, part of Bio-Techne
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NBP1-83726
NBP1-83726-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: QFGNECLNKMHQVMSIEEVERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQEQIELPEVPSEPLPEKIPENVPVK

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (86%), Rat (88%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CHMP6 Antibody

Western Blot: CHMP6 Antibody [NBP1-83726]

Western Blot: CHMP6 Antibody [NBP1-83726]

Western Blot: CHMP6 Antibody [NBP1-83726] - Analysis in control (vector only transfected HEK293T lysate) and CHMP6 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: CHMP6 Antibody [NBP1-83726]

Immunohistochemistry-Paraffin: CHMP6 Antibody [NBP1-83726]

Immunohistochemistry-Paraffin: CHMP6 Antibody [NBP1-83726] - Staining of human appendix shows cytoplasmic positivity in germinal center.

Applications for CHMP6 Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CHMP6

Component of the escrt-iii complex, which is required for multivesicular bodies (mvbs) formation and sorting of endosomal cargo proteins into mvbs. the mvb pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. the escrt-iii complex is probably involved in the concentration of mvb cargo. in the escrt-iii complex, it probably serves as an acceptor for escrt-ii complex on endosomal membranes.

Alternate Names

charged multivesicular body protein 6, chromatin modifying protein 6, Chromatin-modifying protein 6, FLJ11749, Vacuolar protein sorting-associated protein 20, Vps20, VPS20hVps20

Gene Symbol

CHMP6

Additional CHMP6 Products

Product Documents for CHMP6 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CHMP6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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