Chondromodulin-1/LECT1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00011061-B01P

Novus Biologicals, part of Bio-Techne
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H00011061-B01P
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Chondromodulin-1 Antibodies »

Product Specifications

Immunogen

LECT1 (NP_008946.1, 1 a.a. - 334 a.a.) full-length human protein. MTENSDKVPIALVGPDDVEFCSPPAYATLTVKPSSPARLLKVGAVVLISGAVLLLFGAIGAFYFWKGSDSHIYNVHYTMSINGKLQDGSMEIDAGNNLETFKMGSGAEEAIAVNDFQNGITGIRFAGGEKCYIKAQVKARIPEVGAVTKQSISSKLEGKIMPVKYEENSLIWVAVDQPVKDNSFLSSKVLELCGDLPIFWLKPTYPKEIQRERREVVRKIVPTTTKRPHSGPRSNPGAGRLNNETRPSVQEDSQAFNPDNPYHQQEGESMTFDPRLDHEGICCIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVIMPCSWWVARILGMV

Specificity

This product is specific for Human LECT1 purified MaxPab mouse polyclonal antibody (B01P) [Gene ID: 11061].

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Scientific Data Images for Chondromodulin-1/LECT1 Antibody

Western Blot: Chondromodulin-1/LECT1 Antibody [H00011061-B01P]

Western Blot: Chondromodulin-1/LECT1 Antibody [H00011061-B01P]

Western Blot: Chondromodulin-1/LECT1 Antibody [H00011061-B01P] - Analysis of LECT1 expression in transfected 293T cell line by LECT1 polyclonal antibody. Lane 1: LECT1 transfected lysate(36.74 KDa). Lane 2: Non-transfected lysate.

Applications for Chondromodulin-1/LECT1 Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Mouse polyclonal antibody raised against a full-length human LECT1 protein.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Chondromodulin-1

LECT1 encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternate Names

BRICD3, ChM-1, Chondromodulin1, LECT1

Gene Symbol

LECT1

UniProt

NP_008946.1 (Human)

Additional Chondromodulin-1 Products

Product Documents for Chondromodulin-1/LECT1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Chondromodulin-1/LECT1 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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