Chondromodulin-1/LECT1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-59348

Novus Biologicals, part of Bio-Techne
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NBP1-59348
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all Chondromodulin-1 Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to LECT1(leukocyte cell derived chemotaxin 1) The peptide sequence was selected from the N terminal of LECT1. Peptide sequence AIAVNDFQNGITGIRFAGGEKCYIKAQVKARIPEVGAVTKQSISSKLEGK. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for Chondromodulin-1/LECT1 Antibody

Western Blot: Chondromodulin-1/LECT1 Antibody [NBP1-59348]

Western Blot: Chondromodulin-1/LECT1 Antibody [NBP1-59348]

Western Blot: Chondromodulin-1/LECT1 Antibody [NBP1-59348] - Sample Tissue: Human 786-0 Antibody Dilution: 1.0 ug/ml
Western Blot: Chondromodulin-1/LECT1 Antibody [NBP1-59348]

Western Blot: Chondromodulin-1/LECT1 Antibody [NBP1-59348]

Western Blot: Chondromodulin-1/LECT1 Antibody [NBP1-59348] - 721_B cell lysate, concentration 0.2-1 ug/ml.

Applications for Chondromodulin-1/LECT1 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Chondromodulin-1

LECT1 is a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The mature protein promotes chondrocyte growth and inhibits angiogenesis. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development.This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternate Names

BRICD3, ChM-1, Chondromodulin1, LECT1

Gene Symbol

LECT1

UniProt

O75829 (Human)

Additional Chondromodulin-1 Products

Product Documents for Chondromodulin-1/LECT1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Chondromodulin-1/LECT1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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