Chorionic Gonadotropin alpha/beta (hCG) Antibody (HCGab/52) [DyLight 488]

Validated:

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Monoclonal Mouse IgG₁ kappa Clone # HCGab/52

Please see the vial label for concentration. If unlisted please contact technical services.

Purified Chorionic Gonadotropin alpha/beta (hCG) protein

Cytoplasmic, Secreted

This monoclonal antibody is a very special because it reacts ONLY with the intact-HCG and not with either free alpha- or free beta-chain of HCG. HCG is a glycoprotein and is composed of two non-identical, non-covalently linked polypeptide chains designated as the subunit is identical to that of thyroid stimulating hormone (TSH) follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG monoclonal antibody detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.

Pregnancy & Choriocarcinoma Marker

Monoclonal

Mouse

IgG₁ kappa

Protein A or G purified

50mM Sodium Borate

0.05% Sodium Azide

Please see the vial label for concentration. If unlisted please contact technical services.

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Store at 4C in the dark.