CHREBP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-56612

Novus Biologicals, part of Bio-Techne
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NBP2-56612
NBP2-56612-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CHREBP Antibodies »

Product Summary for CHREBP Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: GSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRRITHISAE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CHREBP Antibody

Immunocytochemistry/ Immunofluorescence: CHREBP Antibody [NBP2-56612]

Immunocytochemistry/ Immunofluorescence: CHREBP Antibody [NBP2-56612]

Immunocytochemistry/Immunofluorescence: CHREBP Antibody [NBP2-56612] - Staining of human cell line Hep G2 shows localization to nucleus & cytosol.

Applications for CHREBP Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CHREBP

ChREBP is a transcription factor involved in activating genes that encode enzymes of fatty acid biosynthesis in liver and adipose. The ChREBP protein binds and activates the carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. ChREBP may also play roles in lipid metabolism, obesity, and type II diabetes.

The CHREBP protein is missing in the multisystem developmental disorder, Williams-Beuren syndrome. CHREBP antibodies are useful tools for studying lipid and fatty acid metabolism.

Alternate Names

BHLHD14, CHREBPcarbohydrate-responsive element-binding protein, Class D basic helix-loop-helix protein 14, MIOWS basic-helix-loop-helix leucine zipper protein, MLX interacting protein-like, MLX interactor, MLX-interacting protein-like, MONDOBWilliams-Beuren syndrome chromosomal region 14 protein, WBSCR14Williams-Beuren syndrome chromosome region 14 protein 1, Williams Beuren syndrome chromosome region 14, Williams-Beuren syndrome chromosome region 14 protein 2, WS-bHLHbHLHd14carbohydrate response element binding protein

Gene Symbol

MLXIPL

Additional CHREBP Products

Product Documents for CHREBP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CHREBP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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