CHRNB3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-94886

Novus Biologicals, part of Bio-Techne
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NB100-94886
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all Nicotinic Acetylcholine R beta 3/CHRNB3 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-SRHVKKEHFISQ corresponding to internal region according to NP_000740.1.

Epitope

C-SRHVKKEHFISQ

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Theoretical MW

53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CHRNB3 Antibody

Western Blot: CHRNB3 Antibody [NB100-94886]

Western Blot: CHRNB3 Antibody [NB100-94886]

Western Blot: CHRNB3 Antibody [NB100-94886] - Analysis of CHRNB3 using this antibody at 1 ug/ml in Human Cerebellum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for CHRNB3 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:16000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 50 kDa band observed in human brain (cerebellum) lysates (calculated MW of 52.7 kDa band according to NP_000740.1).
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Nicotinic Acetylcholine R beta 3/CHRNB3

CHRNB3 is associated with subjective responses to tobacco. Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator). Observational study and genome-wide association study of gene-disease association. (HuGE Navigator). Observational study of gene-disease association. (HuGE Navigator). absence of differences in the pharmacological profile of nicotinic receptor alpha3beta4 argues against role for incorporated beta3 subunit in formation of agonist binding sites while changes in channel kinetics suggest important effect on receptor gating

Long Name

Nicotinic Acetylcholine Receptor beta 3

Alternate Names

CHRNB3, NAChRB3

Entrez Gene IDs

1142 (Human); 108043 (Mouse); 171131 (Rat)

Gene Symbol

CHRNB3

UniProt

Q05901 (Human)

Additional Nicotinic Acetylcholine R beta 3/CHRNB3 Products

Product Documents for CHRNB3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CHRNB3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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