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Cited-2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-88786

Novus Biologicals, part of Bio-Techne
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NBP2-88786

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

Product Summary for Cited-2 Antibody

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of human Cited-2. Peptide sequence: HIHYGAGNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVA The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for Cited-2 Antibody

Western Blot: Cited-2 Antibody [NBP2-88786]

Western Blot: Cited-2 Antibody [NBP2-88786]

Western Blot: Cited-2 Antibody [NBP2-88786] - WB Suggested Anti-CITED2 Antibody Titration: 0.2-1 ug/ml. Positive Control: Human brain
Immunohistochemistry-Paraffin: Cited-2 Antibody [NBP2-88786]

Immunohistochemistry-Paraffin: Cited-2 Antibody [NBP2-88786]

Immunohistochemistry-Paraffin: Cited-2 Antibody [NBP2-88786] - Rabbit Anti-CITED2 Antibody. Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue. Observed Staining: Cytoplasmic. Primary Antibody Concentration: 1:100.

Applications for Cited-2 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cited-2

CITED2 is a cAMP-responsive element-binding protein (CBP)/p300 interacting transcriptional modulator. CITED-2 has been proposed as a negative regulator for HIF-1 alpha, as it is thought to interfere with the binding of transcription factors HIF-1a and STAT2 to p300/CBP. Recruitment of CBP/p300 by HIF-1 is essential for the transcriptional response to hypoxia.

CITED 2 antibodies are useful tools for research on hypoxic response mechanisms.

Long Name

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

Alternate Names

Cited2, MRG-1, MSG-related protein 1, P35srj

Gene Symbol

CITED2

Additional Cited-2 Products

Product Documents for Cited-2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Cited-2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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