Claudin-1 Antibody (SR1308)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21736

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21736-100ul
NBP3-21736-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1308

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Claudin-1 Antibodies »

Product Summary for Claudin-1 Antibody (SR1308)

Immunogen

A synthesized peptide derived from human Claudin-1 (Uniprot #: O95832)

Specificity

Detects endogenous levels of total Claudin-1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

19 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Claudin-1 Antibody (SR1308)

Western Blot: Claudin-1 Antibody (SR1308) [NBP3-21736] -

Western Blot: Claudin-1 Antibody (SR1308) [NBP3-21736] - Western blot analysis using NBP3-21736 in A431 cell lysate.

Applications for Claudin-1 Antibody (SR1308)

Application
Recommended Usage

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Claudin-1

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.

Alternate Names

Claudin1, CLD1, CLDN1, SEMP1

Gene Symbol

CLDN1

Additional Claudin-1 Products

Product Documents for Claudin-1 Antibody (SR1308)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Claudin-1 Antibody (SR1308)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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