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Claudin-1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB120-15098

Novus Biologicals, part of Bio-Techne
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NB120-15098
NB120-15098-0.1ml

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

Product Summary for Claudin-1 Antibody

Immunogen

Synthetic peptide (Human) (C terminal).

Localization

Cell Membrane, Cytoplasmic

Specificity

Claudin 1

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Claudin-1 Antibody

Immunohistochemistry-Paraffin: Claudin-1 Antibody [NB120-15098]

Immunohistochemistry-Paraffin: Claudin-1 Antibody [NB120-15098]

Immunohistochemistry-Paraffin: Claudin-1 Antibody [NB120-15098] - Formalin fixed paraffin embedded human skin stained with Claudin 1 antibody (NB120-15098).

Applications for Claudin-1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50-1:100

Immunohistochemistry-Paraffin

1:50-1:100
Application Notes
IHC-P: recommended pretreatment of citrate buffer, pH 6.0. Recommended incubation time of 30 min at RT.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 0.2% BSA, Tween-20

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Claudin-1

Claudin 1-8 proteins are a family of transmembrane proteins associated with tight junctions. Tight junctions are specialized regions of cell to cell contact; made up of networking strands to act as a molecular gasket for preventing the leakage of ions, water etc. between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Different tissues exhibit different Claudin composition.

Alternate Names

Claudin1, CLD1, CLDN1, SEMP1

Entrez Gene IDs

9076 (Human); 12737 (Mouse); 65129 (Rat)

Gene Symbol

CLDN1

Additional Claudin-1 Products

Product Documents for Claudin-1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Claudin-1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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