Claudin-16 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38777

Novus Biologicals, part of Bio-Techne
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NBP2-38777
NBP2-38777-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Claudin-16 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: LFKDVGPERNYPYSLRKAYSAAGVSMAKSYSAPRTETAKMYAVDTRV

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%), Rat (89%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Claudin-16 Antibody

Immunohistochemistry-Paraffin: Claudin-16 Antibody [NBP2-38777]

Immunohistochemistry-Paraffin: Claudin-16 Antibody [NBP2-38777]

Immunohistochemistry-Paraffin: Claudin-16 Antibody [NBP2-38777] - Staining of human lymph node shows low expression as expected.
Immunohistochemistry-Paraffin: Claudin-16 Antibody [NBP2-38777]

Immunohistochemistry-Paraffin: Claudin-16 Antibody [NBP2-38777]

Immunohistochemistry-Paraffin: Claudin-16 Antibody [NBP2-38777] - Staining of human kidney shows high expression.
Immunohistochemistry-Paraffin: Claudin-16 Antibody [NBP2-38777]

Immunohistochemistry-Paraffin: Claudin-16 Antibody [NBP2-38777]

Immunohistochemistry-Paraffin: Claudin-16 Antibody [NBP2-38777] - Staining in human kidney and lymph node tissues using anti-CLDN16 antibody. Corresponding CLDN16 RNA-seq data are presented for the same tissues.

Applications for Claudin-16 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Claudin-16

Claudins are transmembrane proteins with four membrane-spanning regions that serve as the major cell-adhesion molecules of tight junctions. Tight junctions restrict the flow of ions and aqueous molecules between cells, and their permeability is determined by the profile of claudin expression and arrangement of claudins with other proteins at the paracellular barrier. The combination and proportion of claudins vary among different cell types.

Alternate Names

Claudin16, CLDN16, HOMG3, Paracellin-1, PCLN1

Gene Symbol

CLDN16

UniProt

Q9Y5I7 (Human)

Additional Claudin-16 Products

Product Documents for Claudin-16 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Claudin-16 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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