CLEC-2/CLEC-1B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-93458

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all CLEC-2/CLEC1B Antibodies »

Product Specifications

Immunogen

Peptide with sequence KGHKCSPCDTNWRY corresponding to internal region according to NP_001092901.1, NP_057593.3.

Epitope

KGHKCSPCDTNWRY

Specificity

This antibody is expected to recognize both reported isoforms (NP_001092901.1; NP_057593.3)

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for CLEC-2/CLEC-1B Antibody

Western Blot: CLEC-2/CLEC-1B Antibody [NB100-93458]

Western Blot: CLEC-2/CLEC-1B Antibody [NB100-93458]

Western Blot: CLEC1B Antibody [NB100-93458] - (1ug/ml) staining of human kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for CLEC-2/CLEC-1B Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:1000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 28 kDa band observed in human bone marrow and human kidney lysates (calculated MW of 26.6 kDa band according to NP_001092901.1).
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CLEC-2/CLEC1B

Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells.[supplied by OMIM]

Long Name

C-type Lectin-like Receptor 2

Alternate Names

CLEC1B, CLEC2

Entrez Gene IDs

51266 (Human)

Gene Symbol

CLEC1B

UniProt

NP_001092901.1 (Human)

Additional CLEC-2/CLEC1B Products

Product Documents for CLEC-2/CLEC-1B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CLEC-2/CLEC-1B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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