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CLEC-2/CLEC-1B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24748

Novus Biologicals, part of Bio-Techne
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NBP3-24748

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for CLEC-2/CLEC-1B Antibody

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein CLEC-2/CLEC-1B using the following amino acid sequence: WSVMQRNYLQDENENRTGTLQQLAKRFCQYVVKQSELKGTFKGHKCSPCDTNWRYYGDSCYGFFRHNLTWEESK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CLEC-2/CLEC-1B Antibody

CLEC-2/CLEC-1B Antibody Immunohistochemistry-Paraffin: CLEC-2/CLEC-1B Antibody [NBP3-24748]

Immunohistochemistry-Paraffin: CLEC-2/CLEC-1B Antibody [NBP3-24748]

Staining of human bone marrow shows moderate cytoplasmic positivity in hematopoietic cells.

Applications for CLEC-2/CLEC-1B Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, we recommend using Heat-Induced Epitope Retrieval (HIER) with a pH level of 6. This optimized retrieval method ensures the best results for your experiments.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CLEC-2/CLEC1B

Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells.[supplied by OMIM]

Long Name

C-type Lectin-like Receptor 2

Alternate Names

CLEC1B, CLEC2

Gene Symbol

CLEC1B

Additional CLEC-2/CLEC1B Products

Product Documents for CLEC-2/CLEC-1B Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CLEC-2/CLEC-1B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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