CLN3 Antibody (1G10)

Novus Biologicals, part of Bio-Techne | Catalog # H00001201-M03

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 1G10

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CLN3 Antibodies »

Product Specifications

Immunogen

CLN3 (AAH02394.1, 1 a.a. ~ 438 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MGGCAGSRRRFSDSEGEETVPEPRLPLLDHQGAHWKNAVGFWLLGLCNNFSYVVMLSAAHDILSHKRTSGNQSHVDPGPTPIPHNSSSRFDCNSVSTAAVLLADILPTLVIKLLAPLGLHLLPYSPRVLVSGICAAGSFVLVAFSHSVGTSLCGVVFASISSGLGEVTFLSLTAFYPRAVISWWSSGTGGAGLLGALSYLGLTQAGLSPQQTLLSMLGIPALLLASYFLLLTSPEAQDPGGEEEAESAARQPLIRTEAPESKPGSSSSLSLRERWTVFKGLLWYIVPLVVVYFAEYFINQGLFELLFFWNTSLSHAQQYRWYQMLYQAGVFASRSSLRCCRIRFTWALALLQCLNLVFLLADVWFGFLPSIYLVFLIILYEGLLGGAAYVNTFHNIALETSDEHREFAMAATCISDTLGISLSGLLALPLHDFLCQLS

Specificity

CLN3 (1G10)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for CLN3 Antibody (1G10)

Western Blot: CLN3 Antibody (1G10) [H00001201-M03]

Western Blot: CLN3 Antibody (1G10) [H00001201-M03]

Western Blot: CLN3 Antibody (1G10) [H00001201-M03] - Analysis of CLN3 expression in transfected 293T cell line by CLN3 monoclonal antibody (M03), clone 1G10. Lane 1: CLN3 transfected lysatE (47.623 KDa). Lane 2: Non-transfected lysate.
Sandwich ELISA: CLN3 Antibody (1G10) [H00001201-M03] - Detection limit for recombinant GST tagged CLN3 is 0.3 ng/ml as a capture antibody.

Applications for CLN3 Antibody (1G10)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against transfected lysate and recombinant protein for WB. It has been used for ELISA.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CLN3

This gene encodes a protein that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid-lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs). Many alternatively spliced transcript variants have been found for this gene.

Alternate Names

Batten disease protein, Batten, Spielmeyer-Vogt disease, battenin, BTSMGC102840, ceroid-lipofuscinosis, neuronal 3, JNCL, Protein CLN3

Entrez Gene IDs

1201 (Human)

Gene Symbol

CLN3

OMIM

204200 (Human)

UniProt

AAH02394 (Human)

Additional CLN3 Products

Product Documents for CLN3 Antibody (1G10)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CLN3 Antibody (1G10)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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