CLN6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-05809

Novus Biologicals, part of Bio-Techne
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NBP3-05809-100ul
NBP3-05809-50ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CLN6 Antibodies »

Product Specifications

Immunogen

Produced in rabbits immunized with E. coli-derived Human CLN6 fragment.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for CLN6 Antibody

Immunohistochemistry-Paraffin: CLN6 Antibody [NBP3-05809]

Immunohistochemistry-Paraffin: CLN6 Antibody [NBP3-05809]

Immunohistochemistry-Paraffin: CLN6 Antibody [NBP3-05809] - Staining of human CLN6 in human stomach with rabbit polyclonal antibody at 1:100 dilution.
Immunohistochemistry-Paraffin: CLN6 Antibody [NBP3-05809]

Immunohistochemistry-Paraffin: CLN6 Antibody [NBP3-05809]

Immunohistochemistry-Paraffin: CLN6 Antibody [NBP3-05809] - Staining of human CLN6 in human kidney with rabbit polyclonal antibody at 1:100 dilution.

Applications for CLN6 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:50-1:200

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS

Preservative

0.03% Proclin 300

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CLN6

CLN6, a 311-amino acid protein, has 7 predicted transmembrane domains and is conserved across vertebrates. The CLN6 protein localizes to the endoplasmic reticulum but contributes to lysosomal function. Mutations in the CLN6 gene cause variant late-onset infantile neuronal ceroid lipofuscinosis (vLINCL), a lysosomal storage disorder marked by progressive mental deterioration and blindness; part of a group of severe inherited neurodegenerative disorders affecting children wherein lysosomes accumulate storage material, causing the death of neurons. CLN6 is one of eight proteins, including CLN1-8, that are associated with NCL.

Alternate Names

ceroid-lipofuscinosis neuronal protein 6, ceroid-lipofuscinosis, neuronal 6, late infantile, variant, FLJ20561, HsT18960, nclf, Protein CLN6

Gene Symbol

CLN6

Additional CLN6 Products

Product Documents for CLN6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CLN6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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