Clostridium Difficile Toxin A Antibody

Validated:

Cited:

Unconjugated

Polyclonal Rabbit IgG

5.0 mg/ml

Synthetic peptide corresponding to the amino acids 2123 - 2132 of the native molecule conjugated to Keyhole limpet Haemocyanin. Peptide sequence: CTIDGKKYYFN

CTIDGKKYYFN

Secreted

NB100-62473 is specific for Clostridium difficile Toxin A, a gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density, and the administration of antibiotics. Toxin A (TcdA) is a large exotoxin which is an essential virulence factor for C. difficile infection. TcdA has a molecular weight of 308kD and is a glucosyltransferase, which irreversibly inactivates the Ras family of small GTPases to disrupt many important signalling pathways.

Polyclonal

Rabbit

IgG

Protein G purified

PBS

0.09% Sodium Azide

5.0 mg/ml

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.