CNAP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88202

Novus Biologicals, part of Bio-Techne
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NBP1-88202
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (90%), Rat (92%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CNAP1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: VGTIQCLEEILCEFVQKDELKPAVTQLLWERATEKVACCPLERCSSVMLLGMMARGKPEIVGSNLDTLVSIGLDEKFPQDYRLAQQVCHAIANISDRRKPSLGKRH

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CNAP1 Antibody

Immunocytochemistry/ Immunofluorescence: CNAP1 Antibody [NBP1-88202]

Immunocytochemistry/ Immunofluorescence: CNAP1 Antibody [NBP1-88202]

Immunocytochemistry/Immunofluorescence: CNAP1 Antibody [NBP1-88202] - Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.
CNAP1 Antibody

Western Blot: CNAP1 Antibody [NBP1-88202] -

Western Blot: CNAP1 Antibody [NBP1-88202] -Analysis in human cell line RH-30.
CNAP1 Antibody

Immunohistochemistry-Paraffin: CNAP1 Antibody [NBP1-88202] -

Immunohistochemistry-Paraffin: CNAP1 Antibody [NBP1-88202] - Staining of human tonsil shows moderate cytoplasmic positivity in germinal center cells.
View 3 more images

Applications for CNAP1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CNAP1

CNAP1/hCAP-D2 is a regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condensed chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. It may target the condensin complex to DNA via its C-terminal domain (referenced from Swissprot).

Alternate Names

CAPD2, CAP-D2, Chromosome condensation-related SMC-associated protein 1, Chromosome-associated protein D2, CNAP1XCAP-D2 homolog, hCAP-D2condensin complex subunit 1, KIAA0159chromosome condensation related SMC associated protein 1, Non-SMC condensin I complex subunit D2, non-SMC condensin I complex, subunit D2

Gene Symbol

NCAPD2

Additional CNAP1 Products

Product Documents for CNAP1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CNAP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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