CoCoA Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00057658-B01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CoCoA Antibodies »

Product Specifications

Immunogen

CALCOCO1 (NP_065949.1, 1 a.a. - 691 a.a.) full-length human protein. MEESPLSRAPSRGGVNFLNVARTYIPNTKVECHYTLPPGTMPSASDWIGIFKVEAACVRDYHTFVWSSVPESTTDGSPIHTSVQFQASYLPKPGAQLYQFRYVNRQGQVCGQSPPFQFREPRPMDELVTLEEADGGSDILLVVPKATVLQNQLDESQQERNDLMQLKLQLEGQVTELRSRVQELERALATARQEHTELMEQYKGISRSHGEITEERDILSRQQGDHVARILELEDDIQTISEKVLTKEVELDRLRDTVKALTREQEKLLGQLKEVQADKEQSEAELQVAQQENHHLNLDLKEAKSWQEEQSAQAQRLKDKVAQMKDTLGQAQQRVAELEPLKEQLRGAQELAASSQQKATLLGEELASAAAARDRTIAELHRSRLEVAEVNGRLAELGLHLKEEKCQWSKERAGLLQSVEAEKDKILKLSAEILRLEKAVQEERTQNQVFKTELAREKDSSLVQLSESKRELTELRSALRVLQKEKEQLQEEKQELLEYMRKLEARLEKVADEKWNEDATTEDEEAAVGLSCPAALTDSEDESPEDMRLPPYGLCERGDPGSSPAGPREASPLVVISQPAPISPHLSGPAEDSSSDSEAEDEKSVLMAAVQSGGEEANLLLPELGSAFYDMASGFTVGTLSETSTGGPATPTWKECPICKERFPAESDKDALEDHMDGHFFFSTQDPFTFE

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Scientific Data Images for CoCoA Antibody

Western Blot: CoCoA Antibody [H00057658-B01P]

Western Blot: CoCoA Antibody [H00057658-B01P]

Western Blot: CoCoA Antibody [H00057658-B01P] - Analysis of CALCOCO1 expression in rat brain.
Immunocytochemistry/ Immunofluorescence: CoCoA Antibody [H00057658-B01P]

Immunocytochemistry/ Immunofluorescence: CoCoA Antibody [H00057658-B01P]

Immunocytochemistry/Immunofluorescence: CoCoA Antibody [H00057658-B01P] - Analysis of purified antibody to CALCOCO1 on HeLa cell. (antibody concentration 30 ug/ml)
Western Blot: CoCoA Antibody [H00057658-B01P]

Western Blot: CoCoA Antibody [H00057658-B01P]

Western Blot: CoCoA Antibody [H00057658-B01P] - Analysis of CALCOCO1 expression in transfected 293T cell line by CALCOCO1 polyclonal antibody. Lane 1: CALCOCO1 transfected lysate(76.01 KDa). Lane 2: Non-transfected lysate.
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Applications for CoCoA Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody is useful for Western Blot, Functional

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CoCoA

HPS3 is involved in early stages of melanosome biogenesis and maturation. Defects in HPS3 are the cause of the cocoa (coa) mutant, and of Hermansky-Pudlak syndrome type 3 (HPS3). HPS3 is an autosomal recessive disorder, characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects. This syndrome results from defects of diverse cytoplasmic organelles including melanosomes, platelet dense granules and lysosomes. Ceroid storage in the lungs is associated with pulmonary fibrosis, a common cause of premature death in individuals with HPS.

Alternate Names

calcium binding and coiled-coil domain 1, Calphoglin, Cocoa, Coiled-coil coactivator protein, coiled-coil leucine zipper coactivator 1, inorganic pyrophosphatase activator, KIAA1536calcium-binding and coiled-coil domain-containing protein 1, Sarcoma antigen NY-SAR-3

Gene Symbol

CALCOCO1

UniProt

NP_065949.1 (Human)

Additional CoCoA Products

Product Documents for CoCoA Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CoCoA Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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