CoCoA Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-32154

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP1-32154
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CoCoA Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human CoCoA. The exact sequence is proprietary.

Localization

Cytoplasm, Nucleus

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CoCoA Antibody

Western Blot: CoCoA Antibody [NBP1-32154]

Western Blot: CoCoA Antibody [NBP1-32154]

Western Blot: CoCoA Antibody [NBP1-32154] - Sample(30 ug of whole cell lysate) A:HeLa S3 7.5% SDS PAGE, antibody diluted at 1:500.
Immunocytochemistry/ Immunofluorescence: CoCoA Antibody [NBP1-32154]

Immunocytochemistry/ Immunofluorescence: CoCoA Antibody [NBP1-32154]

Immunocytochemistry/Immunofluorescence: CoCoA Antibody [NBP1-32154] - Sample: HeLa cells were fixed in iced-cold MeOH for 5 min. Green: CALCOCO1 protein stained by CoCoA antibody, Internal diluted at 1:500. Blue: Hoechst 33343 staining.
Immunohistochemistry-Paraffin: CoCoA Antibody [NBP1-32154]

Immunohistochemistry-Paraffin: CoCoA Antibody [NBP1-32154]

Immunohistochemistry-Paraffin: CoCoA Antibody [NBP1-32154] - Paraffin-embedded C2C12 xenograft, using antibody at 1:100 dilution.

Applications for CoCoA Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

10 - 1:500

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CoCoA

HPS3 is involved in early stages of melanosome biogenesis and maturation. Defects in HPS3 are the cause of the cocoa (coa) mutant, and of Hermansky-Pudlak syndrome type 3 (HPS3). HPS3 is an autosomal recessive disorder, characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects. This syndrome results from defects of diverse cytoplasmic organelles including melanosomes, platelet dense granules and lysosomes. Ceroid storage in the lungs is associated with pulmonary fibrosis, a common cause of premature death in individuals with HPS.

Alternate Names

calcium binding and coiled-coil domain 1, Calphoglin, Cocoa, Coiled-coil coactivator protein, coiled-coil leucine zipper coactivator 1, inorganic pyrophosphatase activator, KIAA1536calcium-binding and coiled-coil domain-containing protein 1, Sarcoma antigen NY-SAR-3

Gene Symbol

CALCOCO1

Additional CoCoA Products

Product Documents for CoCoA Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CoCoA Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.