COG2 Antibody (4C8)

Novus Biologicals, part of Bio-Techne | Catalog # H00022796-M09

Novus Biologicals, part of Bio-Techne
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H00022796-M09
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Knockdown Validated, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 4C8

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all COG2 Antibodies »

Product Specifications

Immunogen

COG2 (NP_031383, 639 a.a. ~ 738 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. LSESTHKYYETVSDVLNSVKKMEESLKRLKQARKTTPANPVGPSGGMSDDDKIRLQLALDVEYLGEQIQKLGLQASDIKSFSALAELVAAAKDQATAEQP

Reactivity Notes

Human. Other species not tested.

Specificity

COG2 (4C8)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Scientific Data Images for COG2 Antibody (4C8)

Western Blot: COG2 Antibody (4C8) [H00022796-M09]

Western Blot: COG2 Antibody (4C8) [H00022796-M09]

Western Blot: COG2 Antibody (4C8) [H00022796-M09] - Analysis of COG2 expression in transfected 293T cell line by COG2 monoclonal antibody (M09), clone 4C8. Lane 1: COG2 transfected lysatE (83.2 KDa). Lane 2: Non-transfected lysate.
Western Blot: COG2 Antibody (4C8) [H00022796-M09]

Western Blot: COG2 Antibody (4C8) [H00022796-M09]

Western Blot: COG2 Antibody (4C8) [H00022796-M09] - Western blot analysis of COG2 over-expressed 293 cell line, cotransfected with COG2 Validated Chimera RNAi or non-transfected control. Blot probed with H00022796-M09. GAPDH (36.1 kDa) used as loading control.

Applications for COG2 Antibody (4C8)

Application
Recommended Usage

Western Blot

1:500RNAi Validation
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control. It has also been used for RNAi validation.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: COG2

Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG2 (Ungar et al., 2002 [PubMed 11980916]).[supplied by OMIM]

Alternate Names

component of oligomeric golgi complex 2COG complex subunit 2, conserved oligomeric Golgi complex protein 2, conserved oligomeric Golgi complex subunit 2, LDLCbrefeldin A-sensitive, peripheral Golgi protein, low density lipoprotein receptor defect C complementing, Low density lipoprotein receptor defect C-complementing protein

Entrez Gene IDs

22796 (Human)

Gene Symbol

COG2

OMIM

606974 (Human)

UniProt

NP_031383 (Human)

Additional COG2 Products

Product Documents for COG2 Antibody (4C8)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for COG2 Antibody (4C8)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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