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Collagen V Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-26551

Novus Biologicals, part of Bio-Techne
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NBP1-26551

Key Product Details

Species Reactivity

Validated:

Human, Bovine, Equine

Cited:

Human

Applications

Validated:

ELISA, Immunohistochemistry-Frozen

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.4 mg/ml

Product Specifications

Immunogen

Goats were hyperimmunized with human type V collagen.

Specificity

Reacts with conformational determinants on human type V collagen as demonstrated by ELISA. May react with type V collagen from other species. Exhibits

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Collagen V Antibody

Immunohistochemistry-Paraffin: Collagen V Antibody [NBP1-26551]

Immunohistochemistry-Paraffin: Collagen V Antibody [NBP1-26551]

Immunohistochemistry-Paraffin: Collagen V Antibody [NBP1-26551] - Human gastric cancer tissue was stained with Goat Anti-Type V Collagen-UNLB followed by Swine Anti-Goat IgG(H+L), Human/Rat/Mouse SP ads-HRP.
Immunohistochemistry-Frozen: Collagen V Antibody [NBP1-26551]

Immunohistochemistry-Frozen: Collagen V Antibody [NBP1-26551]

Immunohistochemistry-Frozen: Collagen V Antibody [NBP1-26551] - Frozen newborn mouse cartilage section was stained with Goat Anti-Type V Collagen-UNLB followed by Donkey Anti-Goat IgG(H+L), Mouse/Rat SP ads-AF555 and DAPI.
Immunohistochemistry-Frozen: Collagen V Antibody [NBP1-26551]

Immunohistochemistry-Frozen: Collagen V Antibody [NBP1-26551]

Immunohistochemistry-Frozen: Collagen V Antibody [NBP1-26551] - Frozen newborn mouse cartilage section was stained with Goat Anti-Type V Collagen-UNLB followed by Donkey Anti-Goat IgG(H+L), Multi-Species SP ads-AF555 and DAPI.

Applications for Collagen V Antibody

Application
Recommended Usage

ELISA

1:1000-1:4000

Immunohistochemistry-Frozen

1:20-1:40
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

0.1M BBS (pH 8.2)

Preservative

No Preservative

Concentration

0.4 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Collagen V

Collagens are highly conserved throughout evolution and are characterized by an uninterrupted "Glycine-X-Y" triplet repeat that is a necessary part of the triple helical structure. Type V Collagen is a member of group I Collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V Collagen binds to DNA, heparan sulfate, Thrombospondin, Heparin, and Insulin. Collagen V is composed of several subunits as follows: trimers of two alpha 1(V) and one alpha 2(V) chains in most tissues and trimers of one alpha 1(V), one alpha 2(V), and one alpha 3(V) chains in placenta. Type V Collagen is closely related to type XI Collagen and it is possible that the Collagen chains of types V and XI constitute a single collagen type with tissue specific chain combinations. Mutations in this gene are associated with Ehlers Danlos syndrome, types I and II.

Alternate Names

alpha 1 type V collagen, Collagen 5, collagen alpha-1(V) chain, collagen, type V, alpha 1, Collagen-5, EC 2.7.7.6, EC 6.1.1

Gene Symbol

COL5A1

Additional Collagen V Products

Product Documents for Collagen V Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Collagen V Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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