Complement C6 Antibody (056B-214.2.4.2)

Validated:

Unconjugated

Monoclonal Mouse IgG₁ Clone # 056B-214.2.4.2

1.0 mg/ml

Purified human C6

NB100-64337 recognizes complement component 6 (C6), a 104 kDa member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C-terminus of the C5b alpha-chain, anchoring the molecule to the membrane; they also binds complement component 7. This enables the formation of the C5b-7 precursor complex. C5b-7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC). Deficiency of C6 results in susceptibility to bacterial infection. NB100-64337 recognizes MAC.

Monoclonal

Mouse

IgG₁

Protein A purified

Borate buffered saline

0.1% Sodium Azide

1.0 mg/ml

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.