Complement Component C5aR1 Antibody (3A7) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-26470

Recombinant monoclonal antibody expressed in HEK293F cells
Novus Biologicals, part of Bio-Techne
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NBP3-26470-100ul
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Key Product Details

Species Reactivity

Human

Applications

ELISA

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG1 Clone # 3A7

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Complement Component C5aR1 Antibodies »

Product Specifications

Immunogen

Recombinant Human Complement Component C5aR1 protein [UniProt P21730]

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Scientific Data Images for Complement Component C5aR1 Antibody (3A7) - BSA Free

Complement Component C5aR1 Antibody (3A7)

ELISA: Complement Component C5aR1 Antibody (3A7) [NBP3-26470] -

ELISA: Complement Component C5aR1 Antibody (3A7) [NBP3-26470] - The Binding Activity of Human Complement Component C5aR1 with Complement Component C5aR1 Antibody.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human Complement Component C5aR1 at 10 ug/mL can bind Complement Component C5aR1 Antibody, the EC50 is 1.239-3.760 ng/mL.

Applications for Complement Component C5aR1 Antibody (3A7) - BSA Free

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50% Glycerol, 0.01M PBS, PH 7.4

Format

BSA Free

Preservative

0.03% Proclin 300

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -70C. Avoid freeze-thaw cycles.

Background: Complement Component C5aR1

The human anaphylatoxin C5a is a 74 residue glycopeptide which is generated by proteolytic cleavage of the complement factor C5 in the course of complement activation. A variety of biological effects evoked by C5a can be demonstrated, rendering this molecule an important mediartor of inflammation, with granulocytes and macrophages as the main target cells. All cellular responses to C5a are specifically mediated by interactions with the membrane bound C5a receptor, a seven transmembrane GTP binding coupled receptor that belongs to the rhodopsin supergene family. C5a receptor 1 expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract. ESTs have been isolated from B cell/lung/testis, nerve, and placenta libraries.

Long Name

Complement Component C5a Receptor 1

Alternate Names

C5AR1, CD88, Complement Component C5a R1

Gene Symbol

C5AR1

Additional Complement Component C5aR1 Products

Product Documents for Complement Component C5aR1 Antibody (3A7) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Complement Component C5aR1 Antibody (3A7) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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