Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # OTI7C9

Concentration

1 mg/ml

View all Complement Factor I Antibodies »

Product Summary for Complement Factor I Antibody (OTI7C9)

Immunogen

Human recombinant protein fragment corresponding to amino acids 340-583 of human CFI(NP_000195) produced in E.coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Theoretical MW

63.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Complement Factor I Antibody (OTI7C9)

Western Blot: Complement Factor I Antibody (OTI7C9) [NBP2-46264]

Western Blot: Complement Factor I Antibody (OTI7C9) [NBP2-46264]

Western Blot: Complement Factor I Antibody (7C9) [NBP2-46264] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Complement Factor 1.
Immunohistochemistry-Paraffin: Complement Factor I Antibody (OTI7C9) [NBP2-46264]

Immunohistochemistry-Paraffin: Complement Factor I Antibody (OTI7C9) [NBP2-46264]

Immunohistochemistry-Paraffin: Complement Factor I Antibody (OTI7C9) [NBP2-46264] - Complement Factor I Antibody (7C9) [NBP2-46264] - Analysis of Adenocarcinoma of Human ovary tissue, dilution 1:150
Immunohistochemistry-Paraffin: Complement Factor I Antibody (OTI7C9) [NBP2-46264]

Immunohistochemistry-Paraffin: Complement Factor I Antibody (OTI7C9) [NBP2-46264]

Immunohistochemistry-Paraffin: Complement Factor I Antibody (OTI7C9) [NBP2-46264] - Complement Factor I Antibody (7C9) [NBP2-46264] - Analysis of Human Kidney tissue, dilution 1:150
View 1 more images

Applications for Complement Factor I Antibody (OTI7C9)

Application
Recommended Usage

Immunohistochemistry

1:150

Western Blot

1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Complement Factor I

Factor I is a plasma protein of molecular weight 88 kDa, consisting of two disulphide linked chains of 50 and 38 kDa. Factor I is a serine protease with a high degree of specificity for C3b and C4b. It has a requirement for protein cofactors for cleavage of these complement proteins, Factor H, CR1 or MCP are required for C3b cleavage and C4bp or CR1 for C4b cleavage.

Alternate Names

C3b Inactivator, CFI

Gene Symbol

CFI

Additional Complement Factor I Products

Product Documents for Complement Factor I Antibody (OTI7C9)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Complement Factor I Antibody (OTI7C9)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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