Connexin 30.1/GJB5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-84333

Novus Biologicals, part of Bio-Techne
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NBP1-84333
NBP1-84333-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Connexin 30.1/GJB5 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: KRCHECLAARKAQAMCTGHHPHGTTSSCKQDDLLSGDLIFLGSDSHPPLLPDRPRDHVKK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Connexin 30.1/GJB5 Antibody

Western Blot: Connexin 30.1/GJB5 Antibody [NBP1-84333]

Western Blot: Connexin 30.1/GJB5 Antibody [NBP1-84333]

Western Blot: Connexin 30.1/GJB5 Antibody [NBP1-84333] - Analysis in control (vector only transfected HEK293T lysate) and GJB5 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: Connexin 30.1/GJB5 Antibody [NBP1-84333]

Immunohistochemistry-Paraffin: Connexin 30.1/GJB5 Antibody [NBP1-84333]

Immunohistochemistry-Paraffin: Connexin 30.1/GJB5 Antibody [NBP1-84333] - Staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.

Applications for Connexin 30.1/GJB5 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Connexin 30.1/GJB5

GJB5, also known as Gap junction beta-5 protein, is a 273 amino acid protein that is 31 kDa. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, that provide direct intracellular communication. Current research is being performed on this proteins involvement in erythrokeratodermia variabilis, peripheral neuropathy, neuropathy, neuronitis, erythrokeratoderma, and hearing loss. This protein has been linked to signaling in Gap junctions pathway and interacting GSK3B protein.

Alternate Names

CX31.1, GJB5

Gene Symbol

GJB5

Additional Connexin 30.1/GJB5 Products

Product Documents for Connexin 30.1/GJB5 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Connexin 30.1/GJB5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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