Connexin 43/GJA1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38234

Novus Biologicals, part of Bio-Techne
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NBP2-38234
NBP2-38234-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (97%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Connexin 43/GJA1 Antibodies »

Product Summary for Connexin 43/GJA1 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: EQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNSKKLAAGHELQPLAIVDQRPSSRASSRASSRPR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Connexin 43/GJA1 Antibody

Immunohistochemistry-Paraffin: Connexin 43/GJA1 Antibody [NBP2-38234]

Immunohistochemistry-Paraffin: Connexin 43/GJA1 Antibody [NBP2-38234]

Immunohistochemistry-Paraffin: Connexin 43/GJA1 Antibody [NBP2-38234] - Staining in human parathyroid gland and liver tissues using anti-GJA1 antibody. Corresponding GJA1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Connexin 43/GJA1 Antibody [NBP2-38234]

Immunohistochemistry-Paraffin: Connexin 43/GJA1 Antibody [NBP2-38234]

Immunohistochemistry-Paraffin: Connexin 43/GJA1 Antibody [NBP2-38234] - Staining of human Skin shows strong membranous positivity in epidermal cells.
Immunohistochemistry-Paraffin: Connexin 43/GJA1 Antibody [NBP2-38234]

Immunohistochemistry-Paraffin: Connexin 43/GJA1 Antibody [NBP2-38234]

Immunohistochemistry-Paraffin: Connexin 43/GJA1 Antibody [NBP2-38234] - Staining of human liver shows low expression as expected.
View 3 more images

Applications for Connexin 43/GJA1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Connexin 43/GJA1

Connexin 43/GJA1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. GJA1 is the major cardiac gap junction protein, which is thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. GJA1 is targeted by several protein kinases that regulate myocardial cell cell coupling. A related intronless GJA1 pseudogene, GJA1P, has been mapped to chromosome 5.

Alternate Names

CX43, GJA1, GJAL, ODDD, ODOD, SDTY3

Gene Symbol

GJA1

UniProt

P17302

Additional Connexin 43/GJA1 Products

Product Documents for Connexin 43/GJA1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Connexin 43/GJA1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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