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Connexin 43/GJA1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24691

Novus Biologicals, part of Bio-Techne
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NBP3-24691

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for Connexin 43/GJA1 Antibody

Immunogen

KLH conjugated synthetic peptide between 107-138 amino acids from the N-terminal region of human Connexin 43/GJA1.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Connexin 43/GJA1 Antibody

Western Blot: Connexin 43/GJA1 Antibody [NBP3-24691] -

Western Blot: Connexin 43/GJA1 Antibody [NBP3-24691] - Western blot analysis using a Connexin 43 polyclonal antibody (Product # NBP3-24691) in CEM cell lysates (35 ug per lane).

Immunohistochemistry-Paraffin: Connexin 43/GJA1 Antibody [NBP3-24691] -

Immunohistochemistry-Paraffin: Connexin 43/GJA1 Antibody [NBP3-24691] - Immunohistochemical analysis of formalin-fixed, paraffin-embedded human cancer tissue using a Connexin 43 polyclonal antibody (Product # NBP3-24691), followed by HRP-conjugated secondary antibody and DAB staining.

Western Blot: Connexin 43/GJA1 Antibody [NBP3-24691] -

Western Blot: Connexin 43/GJA1 Antibody [NBP3-24691] - Western blot analysis using a Connexin 43 polyclonal antibody (Product # NBP3-24691) in mouse brain tissue lysates (35 ug per lane).

Applications for Connexin 43/GJA1 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:50 - 1:100

Western Blot

1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.09% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Connexin 43/GJA1

Connexin 43/GJA1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. GJA1 is the major cardiac gap junction protein, which is thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. GJA1 is targeted by several protein kinases that regulate myocardial cell cell coupling. A related intronless GJA1 pseudogene, GJA1P, has been mapped to chromosome 5.

Alternate Names

CX43, GJA1, GJAL, ODDD, ODOD, SDTY3

Gene Symbol

GJA1

Additional Connexin 43/GJA1 Products

Product Documents for Connexin 43/GJA1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Connexin 43/GJA1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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