Connexin 50/GJA8 Antibody (8A10)

Novus Biologicals, part of Bio-Techne | Catalog # H00002703-M02-100ug

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 8A10

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Connexin 50/GJA8 Antibodies »

Product Specifications

Immunogen

GJA8 (NP_005258, 301 a.a. ~ 410 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. EEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAERLTTEEQEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPELTT

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for Connexin 50/GJA8 Antibody (8A10)

Western Blot: Connexin 50/GJA8 Antibody (8A10) [H00002703-M02-100ug]

Western Blot: Connexin 50/GJA8 Antibody (8A10) [H00002703-M02-100ug]

Western Blot: Connexin 50/GJA8 Antibody (8A10) [H00002703-M02-100ug] - Detection against Immunogen (37.84 KDa) .
ELISA: Connexin 50/GJA8 Antibody (8A10) [H00002703-M02-100ug]

ELISA: Connexin 50/GJA8 Antibody (8A10) [H00002703-M02-100ug]

ELISA: Connexin 50/GJA8 Antibody (8A10) [H00002703-M02-100ug] - Detection limit for recombinant GST tagged GJA8 is 0.03 ng/ml as a capture antibody.

Applications for Connexin 50/GJA8 Antibody (8A10)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Connexin 50/GJA8

The 433 amino acid long, 48 kDA transmembrane connexin, gap junction alpha-8 protein encoded by the GJA8 gene is critical in growth and development of lens fiber cells. Mutations in the GJA8 gene may lead to zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome. The GJA8 gene has been linked to myopia, microphthalmia, neuronitis, cycstic fibrosis, neuopathy, cervical adenocarcinoma, and juvenile myoclonic epilepsy. The GJA8 gene interacts with TJP1, MIP, MED14, GJA1, and GJB1 to participate in pathways such as gap junction assembly, membrane trafficking, and connexin synthesis.

Alternate Names

CAE1, CX50, CZP1, GJA8, MP70

Entrez Gene IDs

2703 (Human)

Gene Symbol

GJA8

OMIM

116200 (Human)

UniProt

NP_005258

Additional Connexin 50/GJA8 Products

Product Documents for Connexin 50/GJA8 Antibody (8A10)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Connexin 50/GJA8 Antibody (8A10)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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