Contactin-1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-68900

Novus Biologicals, part of Bio-Techne
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NBP2-68900
NBP2-68900-25ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Mouse (92%), Rat (92%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Contactin-1 Antibodies »

Product Summary for Contactin-1 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: TNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Contactin-1 Antibody

Immunohistochemistry: Contactin-1 Antibody [NBP2-68900]

Immunohistochemistry: Contactin-1 Antibody [NBP2-68900]

Immunohistochemistry: Contactin-1 Antibody [NBP2-68900] - Immunohistochemical staining of human hippocampus shows moderate positivity in neuropil.

Applications for Contactin-1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
Recommended conditions for IHC,Retrieval method: HIER pH6
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Contactin-1

Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth.; SUBUNIT: Monomer. Interacts with CNTNAP1 in cis form. Binds to the carbonic-anhydrase like domain of protein-tyrosine phosphatase zeta. Interacts with NOTCH1 and TNR.

Alternate Names

CNTN1, Contactin1, F11, F3cam

Gene Symbol

CNTN1

Additional Contactin-1 Products

Product Documents for Contactin-1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Contactin-1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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