Key Product Details

Validated by

Biological Validation

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all COP9 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residues 325 and 375 of human COP9 constitutive photomorphogenic homolog subunit 3 using the numbering given in entry NP_003644.2 (GeneID 8533).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for COP9 Antibody

Western Blot: COP9 Antibody [NB100-365]

Western Blot: COP9 Antibody [NB100-365]

Western Blot: COP9 Antibody [NB100-365] - Detection of Human CSN3 by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa and 293T cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-CSN3 antibody NB100-365 used for WB at 0.05 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Western Blot: COP9 Antibody [NB100-365]

Western Blot: COP9 Antibody [NB100-365]

Western Blot: COP9 Antibody [NB100-365] - Whole cell lysate (50 ug - E; 10 ug - T) from mock transfected (E) or CSN3 transfected (T) HEK293T cells. Antibody used at the indicated concentration.

Applications for COP9 Antibody

Application
Recommended Usage

Western Blot

1:2000-1:20000
Application Notes
By Western blot, this antibody recognizes a band at ~40 kDa, representing CSN3 protein. *The investigator should determine the optimal working dilution for a specific application.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: COP9

COP9 signalosome is a conserved protein composed of eight subunits. Individual subunits of the complex have been linked to various signal transduction pathways leading to gene expression and cell cycle control. CSN3 encodes the third subunit of COP9 signalosome. CSN3 is important for maintaining the integrity of the COP9 signalosome and crucial for the survival of epiblast cells.

Alternate Names

COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis), COP9 signalosome complex subunit 3, CSN3COP9 complex subunit 3, JAB1-containing signalosome subunit 3, SGN3COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 3, Signalosome subunit 3

Entrez Gene IDs

8533 (Human)

Gene Symbol

COPS3

UniProt

NP_003644.2 (Human)

Additional COP9 Products

Product Documents for COP9 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for COP9 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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