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Corticotropin Releasing Factor Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-41273

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

Product Summary for Corticotropin Releasing Factor Antibody - BSA Free

Immunogen

Antibody was raised against a 16 amino acid peptide near the amino terminus of human CRH. The immunogen is located within amino acids 30 - 80 of CRH. Amino Acid Squence: FQPPPQSEQPQQPQAR

Specificity

CRH antibody is human specific.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

29 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Corticotropin Releasing Factor Antibody - BSA Free

Western Blot: Corticotropin Releasing Factor AntibodyBSA Free [NBP2-41273]

Western Blot: Corticotropin Releasing Factor AntibodyBSA Free [NBP2-41273]

Western Blot: Corticotropin Releasing Factor Antibody [NBP2-41273] - Analysis of CRH in human placenta tissue lysate with CRH antibody at (A) 1 and (B) 2 ug/ml.
Immunohistochemistry-Paraffin: Corticotropin Releasing Factor Antibody - BSA Free [NBP2-41273]

Immunohistochemistry-Paraffin: Corticotropin Releasing Factor Antibody - BSA Free [NBP2-41273]

Immunohistochemistry-Paraffin: Corticotropin Releasing Factor Antibody [NBP2-41273] - Human brain tissue with Corticotropin Releasing Factor antibody at 5 ug/mL.

Immunohistochemistry: Corticotropin Releasing Factor Antibody [NBP2-41273] -

Immunohistochemistry: Corticotropin Releasing Factor Antibody [NBP2-41273] - Human brain tissue antibody at 20 ug/mL.

Applications for Corticotropin Releasing Factor Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

1-2 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Corticotropin Releasing Factor

Corticotropin-releasing hormone (CRH) is a 41-amino acid peptide derived from a 191-amino acid preprohormone. CRH issecreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in CRH hasbeen observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin dificiency hasmultiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to productionin the hypothalamus, CRH is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed inthe placenta. In the placenta CRH is a marker that determines the length of gestation and the timing of parturitionand delivery. A rapid increase in circulating levels of CRH occurs at the onset of parturition, suggesting that, inaddition to its metabolic functions, CRH may act as a trigger for parturition. (provided by RefSeq)

Alternate Names

corticoliberin, corticotropin releasing hormone, Corticotropin-releasing hormone, CRFCorticotropin-releasing factor

Gene Symbol

CRH

Additional Corticotropin Releasing Factor Products

Product Documents for Corticotropin Releasing Factor Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Corticotropin Releasing Factor Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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