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CPOX Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-58431

Novus Biologicals, part of Bio-Techne
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NBP2-58431
NBP2-58431-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (91%), Rat (92%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for CPOX Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: CDDYFFIAHRGERRGIGGIFFDDLDSPSKEEVFRFVQSCARAVVPSYIPLVKKHCDDSFTPQEKLWQQLRRGRYVEFNLLYDRGTKFGLFTPGSRIESILMSLPLTARWEYMHSPSENSKEAEILEVLRHPRDWV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CPOX Antibody

Immunocytochemistry/ Immunofluorescence: CPOX Antibody [NBP2-58431]

Immunocytochemistry/ Immunofluorescence: CPOX Antibody [NBP2-58431]

Immunocytochemistry/Immunofluorescence: CPOX Antibody [NBP2-58431] - Staining of human cell line U-2 OS shows localization to mitochondria.

Applications for CPOX Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CPOX

The protein encoded by the CPOX gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is solubleand found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation ofcoproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditarycoproporphyria (HCP).

Alternate Names

Coprogen oxidase, coproporphyrinogen oxidase, Coproporphyrinogenase, coproporphyrinogen-III oxidase, mitochondrial, COX, CPO, CPXcoproporphyrinogen oxidase (coproporphyria, harderoporphyria), EC 1.3.3.3, HCP

Gene Symbol

CPOX

Additional CPOX Products

Product Documents for CPOX Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CPOX Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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