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CRHR1/CRF1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16010

Novus Biologicals, part of Bio-Techne
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NBP2-16010

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Mammal

Predicted:

Rabbit (100%), Rat (100%), Rhesus Macaque (100%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human CRHR1/CRF1. The exact sequence is proprietary.

Reactivity Notes

Mammal reactivity reported in scientific literature (PMID:33344730)

Localization

Cell membrane

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

51 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CRHR1/CRF1 Antibody

Western Blot: CRHR1/CRF1 Antibody [NBP2-16010]

Western Blot: CRHR1/CRF1 Antibody [NBP2-16010]

Western Blot: CRHR1/CRF1 Antibody [NBP2-16010] - Sample (50 ug of whole cell lysate) A: Mouse brain 10% SDS PAGE diluted at 1:500 The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.
Immunohistochemistry-Paraffin: CRHR1/CRF1 Antibody [NBP2-16010]

Immunohistochemistry-Paraffin: CRHR1/CRF1 Antibody [NBP2-16010]

Immunohistochemistry-Paraffin: CRHR1/CRF1 Antibody [NBP2-16010] - HeLa xenograft, using CRFR1 antibody at 1:500 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.

Applications for CRHR1/CRF1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Reviewed Applications

Read 1 review rated 4 using NBP2-16010 in the following applications:

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CRHR1

This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants.

Long Name

Corticotropin Releasing Hormone Receptor 1

Alternate Names

CHR-R1, CRF1, CRFR, CRFR1

Gene Symbol

CRHR1

UniProt

Additional CRHR1 Products

Product Documents for CRHR1/CRF1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CRHR1/CRF1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.