CRIM1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-80799

Novus Biologicals, part of Bio-Techne
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NBP1-80799
NBP1-80799-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse, Rat

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC, Immunohistochemistry-Frozen

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CRIM1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LTEYEAGVCEDENWTDDQLLGFKPCNENLIAGCNIINGKCECNTIRTCSNPFEFPSQDMCLSALKRIEEEKPDCSKARCEVQFSPRCPEDSVLIEGYAPPGECCPLP

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (88%). Mouse reactivity reported in scientific literature (PMID: 26545120)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CRIM1 Antibody

CRIM1 Antibody

Immunohistochemistry-Paraffin: CRIM1 Antibody [NBP1-80799] -

Immunohistochemistry-Paraffin: CRIM1 Antibody [NBP1-80799] - Analysis in human placenta and liver tissues using NBP1-80799 antibody. Corresponding CRIM1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: CRIM1 Antibody [NBP1-80799]

Immunohistochemistry-Paraffin: CRIM1 Antibody [NBP1-80799]

Immunohistochemistry-Paraffin: CRIM1 Antibody [NBP1-80799] - Staining of human liver shows low expression as expected.
CRIM1 Antibody

Immunohistochemistry-Paraffin: CRIM1 Antibody [NBP1-80799] -

Immunohistochemistry-Paraffin: CRIM1 Antibody [NBP1-80799] -Staining of human placenta shows moderate cytoplasmic positivity in trophoblastic cells.
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Applications for CRIM1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
IHC-P HIER pH6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CRIM1

CRIM1, also known as cysteine rich motor neuron 1, is a type I transmembrane glycoprotein containing an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain. CRIM1 CRRs are similar to those in the BMP-binding antagonists such as Chordin. CRIM1 can interact with TGF-beta family ligands to modulate TGF-beta family ligand functions.

Long Name

Cysteine Rich Motor Neuron 1 Protein

Alternate Names

S52

Entrez Gene IDs

51232 (Human)

Gene Symbol

CRIM1

UniProt

Q9NZV1

Additional CRIM1 Products

Product Documents for CRIM1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CRIM1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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