Key Product Details

Species Reactivity

Human, Primate

Applications

Blockade of Receptor-ligand Interaction, CyTOF-ready, ELISA Capture (Matched Antibody Pair), ELISA Detection (Matched Antibody Pair), ELISA Standard (Matched Pair), Flow Cytometry, Immunocytochemistry

Label

Janelia Fluor 646

Antibody Source

Recombinant Monoclonal Mouse IgG1 Clone # 89633

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Cripto Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human Cripto-1
Arg38-Tyr188
Accession # P13385

Specificity

Detects human and primate Cripto-1 in ELISAs. In sandwich immunoassays, no cross-reactivity with recombinant mouse Cripto-1, recombinant human (rh) EGF, rhTGF‑ alpha, rhTGF-beta 1, rhTGF-beta 2, rhTGF-beta 3, or rhCryptic is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for CRIPTO Antibody (89633) [Janelia Fluor® 646]

Application
Recommended Usage

Blockade of Receptor-ligand Interaction

Optimal dilutions of this antibody should be experimentally determined.

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

ELISA Capture (Matched Antibody Pair)

Optimal dilutions of this antibody should be experimentally determined.

ELISA Detection (Matched Antibody Pair)

Optimal dilutions of this antibody should be experimentally determined.

ELISA Standard (Matched Pair)

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Cripto

Teratocarcinoma-derived growth factor 1 (TDGF1), also known as CRIPTO, is expressed both in ES cells and during the early phases of embryo development. During development, CRIPTO is thought to play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. In adults, it is reactivated in a wide range of epithelial cancers.

CRIPTO-1 antibodies are useful tools for studying embryonic development and certian cancers.

Long Name

Teratocarcinoma-derived Growth Factor/Cripto Growth Factor

Alternate Names

CFC-2, TDGF-1, TDGF1

Gene Symbol

TDGF1

Additional Cripto Products

Product Documents for CRIPTO Antibody (89633) [Janelia Fluor® 646]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CRIPTO Antibody (89633) [Janelia Fluor® 646]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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