CRISP-2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76277

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all CRISP-2 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human CRISP2. The immunogen is located within the first 50 amino acids of CRISP2. Amino Acid Squence: CPSLPAEGKDPAFTAL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CRISP-2 Antibody - BSA Free

Western Blot: CRISP-2 AntibodyBSA Free [NBP1-76277]

Western Blot: CRISP-2 AntibodyBSA Free [NBP1-76277]

Western Blot: CRISP-2 Antibody [NBP1-76277] - Human testis tissue lysate with CRISP2 antibody at (A) 0.5 and (B) 1 ug/mL.
CRISP-2 Antibody - BSA Free

Immunohistochemistry: CRISP-2 Antibody - BSA Free [NBP1-76277] -

Immunohistochemistry: CRISP-2 Antibody - BSA Free [NBP1-76277] - Immunohistochemistry of CRISP-2 in human testis tissue with CRISP-2 antibody at 10 u/mL.
CRISP-2 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: CRISP-2 Antibody - BSA Free [NBP1-76277] -

Immunocytochemistry/ Immunofluorescence: CRISP-2 Antibody - BSA Free [NBP1-76277] - Immunofluorescence of CRISP in human testis tissue with CRISP antibody at 20 u/mL.

Applications for CRISP-2 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

10 ug/ml

Immunohistochemistry-Paraffin

10 ug/ml

Western Blot

0.5-1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CRISP-2

The cysteine-rich secretory proteins (CRISP) family is a group of four proteins that are strongly expressed in the male reproductive tract and have been implicated in having roles in male fertility. CRISP2, also known as TPX1, has been implicated in the adhesion between spermatids and Sertoli cells, and with CRISP1, is thought to be involved in sperm-egg fusion. CRISP2 has been shown to regulate the Ca2+ influx through ryanodine receptors (RYR) and may influence the acrosome reaction or sperm motility. CRISP2 has also been shown to bind to the mitogen-activated protein kinase kinase kinase 11 (MAP3K11) and localizes to the developing acrosome, suggesting this CRISP2-MAP3K11 complex may have a role in acrosome development.

Long Name

Cysteine-rich Secretory Protein 2

Alternate Names

CRISP2, GAPDL5, TPX1, TSP1

Gene Symbol

CRISP2

UniProt

NP_001135880 (Human)

Additional CRISP-2 Products

Product Documents for CRISP-2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CRISP-2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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