CRM1 Antibody (1J0L10)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15823

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP3-15823-100ul
NBP3-15823-20ul
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 1J0L10

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CRM1 Antibodies »

Product Summary for CRM1 Antibody (1J0L10)

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 972-1071 of human CRM1 (O14980). IFLQEYVANLLKSAFPHLQDAQVKLFVTGLFSLNQDIPAFKEHLRDFLVQIKEFAGEDTSDLFLEEREIALRQADEEKHKRQMSVPGIFNPHEIPEEMCD

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CRM1 Antibody (1J0L10)

Western Blot: CRM1 Antibody (1J0L10) [NBP3-15823]

Western Blot: CRM1 Antibody (1J0L10) [NBP3-15823]

Western Blot: CRM1 Antibody (1J0L10) [NBP3-15823] - Western blot analysis of extracts of various cell lines, using CRM1 antibody (NBP3-15823) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Immunocytochemistry/ Immunofluorescence: CRM1 Antibody (1J0L10) [NBP3-15823]

Immunocytochemistry/ Immunofluorescence: CRM1 Antibody (1J0L10) [NBP3-15823]

Immunocytochemistry/Immunofluorescence: CRM1 Antibody (1J0L10) [NBP3-15823] - Immunofluorescence analysis of NIH-3T3 cells using CRM1 antibody (NBP3-15823). Blue: DAPI for nuclear staining.
Immunohistochemistry-Paraffin: CRM1 Antibody (1J0L10) [NBP3-15823]

Immunohistochemistry-Paraffin: CRM1 Antibody (1J0L10) [NBP3-15823]

Immunohistochemistry-Paraffin: CRM1 Antibody (1J0L10) [NBP3-15823] - Immunohistochemistry of paraffin-embedded mouse spleen using CRM1 antibody (NBP3-15823) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
View 5 more images

Applications for CRM1 Antibody (1J0L10)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50 - 1:200

Immunohistochemistry

1:50 - 1:200

Western Blot

1:500 - 1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 0.05% BSA, 50% glycerol, pH7.3

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CRM1

Official Gene Symbol: XPO1 Gen Bank Accession Number: NP_003391 Gene ID: 7514 (human) Gene Map Locus: 2p16 (human) Nuclear transport receptors of karyopherin/importin-beta superfamily mediate various transport pathways between nucleus and cytoplasm. Exportin-1, a human homolog of yeast CRM1, is a novel karyopherin export receptor that mediates leucine-rich NES-dependent protein export. It interacts with RanGTP through its Ran-binding domain and also with nucleoporins including Nup214, Nup50, Nup42 and Nup159 during the process of exporting NES-containing proteins. It mediates the export of many cellular and viral proteins and ribonucleoproteins including HIV Rev Protein, ERK3, PKI, IRF-5, Cyclin-B, MAPKK, MAPKAP kinase 2, Snurportin, Cap-binding protein, and certain U snRNAs. Reports suggest exportin-1 also has a role in the regulation of NFAT and AP-1.

Long Name

Chromosome Region Maintenence 1 Homolog

Alternate Names

CRM-1, Exp1, Exportin 1, XPO1

Gene Symbol

XPO1

Additional CRM1 Products

Product Documents for CRM1 Antibody (1J0L10)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CRM1 Antibody (1J0L10)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.