CRMP5 Antibody (SR2071)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22160

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22160-100ul
NBP3-22160-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2071

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CRMP5 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human CRMP5 (Uniprot #: Q9BPU6)

Specificity

Detects endogenous levels of total CRMP5

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

61 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CRMP5 Antibody (SR2071)

Western Blot: CRMP5 Antibody (SR2071) [NBP3-22160] -

Western Blot: CRMP5 Antibody (SR2071) [NBP3-22160] - Western blot analysis using NBP3-22160 in SH-SY5Y cell lysate.

Applications for CRMP5 Antibody (SR2071)

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Immunoprecipitation

1:50

Western Blot

1:1000-1:5000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CRMP5

The collapsin response mediator protein (CRMP) family of proteins (also referred to as ULIP6) are a group of neurologic proteins that have been found to play key roles in growth cone guidance during neural development. CRMP5 has relatively low sequence homology with the other four members of the CRMP family. CRMP5 is expressed in the developing nervous system in an expression pattern that resembles CRMP2 and has a peak expression during the first postnatal week. Elevated levels of autoantibody to CRMP5 have been shown to be linked paraneoplastic autoimmune optic neuritis and other paraneoplastic neoplasms. Auto-immunity against CRMP5 expression (predominantly the N-terminal epitopes) is also being investigated as an oncological marker in the respiratory system and in the thymus.

Alternate Names

Collapsin response mediator protein 5, collapsin response mediator protein-5, CRAMCRMP3-associated molecule, CRMP-5FLJ45383, CRMP5UNC33-like phosphoprotein 6, dihydropyrimidinase-like 5, dihydropyrimidinase-related protein 5, DRP-5, Ulip6, ULIP-6

Gene Symbol

DPYSL5

Additional CRMP5 Products

Product Documents for CRMP5 Antibody (SR2071)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CRMP5 Antibody (SR2071)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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