Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all CROP Antibodies »

Product Summary for CROP Antibody

Immunogen

The immunogen recognized by this antibody maps to a region between residue 1 and 50 of human cisplatin resistance-associated overexpressed protein using the numbering given in entry NP_057508.2 (GeneID 51747).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CROP Antibody

Western Blot: CROP Antibody [NB100-74625]

Western Blot: CROP Antibody [NB100-74625]

Western Blot: CROP Antibody [NB100-74625] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Affinity purified rabbit anti-CROP/Luc7A antibody NB100-74625 used for IP at 3 mcg/mg lysate. CROP/Luc7A was also immunoprecipitated by rabbit anti-CROP/Luc7A antibody NB100-74626, which recognizes a downstream epitope.
Immunohistochemistry: CROP Antibody [NB100-74625]

Immunohistochemistry: CROP Antibody [NB100-74625]

Immunohistochemistry: CROP Antibody [NB100-74625] - Sample: FFPE section of human testicular seminoma (left) and mouse colon carcinoma (right). Antibody: Affinity purified rabbit anti-CROP/Luc7A used at a dilution of 1:1,000 (1ug/ml). Detection: DAB
Immunohistochemistry-Paraffin: CROP Antibody [NB100-74625]

Immunohistochemistry-Paraffin: CROP Antibody [NB100-74625]

Immunohistochemistry-Paraffin: CROP Antibody [NB100-74625] - FFPE section of human thyroid carcinoma. Affinity purified rabbit anti-CROP/Luc7A used at a dilution of 1:250.

Applications for CROP Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:100-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: CROP

This gene encodes a cisplatin resistance-associated overexpressed protein (CROP). The N-terminal half of the CROP contains cysteine/histidine motifs and leucine zipper-like repeats, and the C-terminal half is rich in arginine and glutamate residues (RE domain) and arginine and serine residues (RS domain). This protein localizes with a speckled pattern in the nucleus, and could be involved in the formation of splicesome via the RE and RS domains. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Alternate Names

cAMP regulatory element-associated protein 1, cisplatin resistance associated overexpressed protein, cisplatin resistance-associated overexpressed protein, Cisplatin resistance-associated-overexpressed protein, CREAP1, CREAP-1LUC7ACRA, CRE-associated protein 1, CROPFLJ11063, hLuc7A, Luc7A, LUC7-like 3 (S. cerevisiae), luc7-like protein 3, O48, OA48-18, Okadaic acid-inducible phosphoprotein OA48-18

Entrez Gene IDs

51747 (Human)

Gene Symbol

LUC7L3

UniProt

NP_057508.2 (Human)

Additional CROP Products

Product Documents for CROP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CROP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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