CRYBA4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-57040

Novus Biologicals, part of Bio-Techne
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NBP2-57040
NBP2-57040-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CRYBA4 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: MTLQCTKSAGPWKMVVWDEDGFQG

Reactivity Notes

Mouse 88%, Rat 83%

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CRYBA4 Antibody

Immunohistochemistry-Paraffin: CRYBA4 Antibody [NBP2-57040]

Immunohistochemistry-Paraffin: CRYBA4 Antibody [NBP2-57040]

Immunohistochemistry-Paraffin: CRYBA4 Antibody [NBP2-57040] - Staining of eye shows strong positivity in the lens.

Applications for CRYBA4 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CRYBA4

CRYBA4, or Beta-crystallin A4, consists of a 196 amino acid isoform that is 22 kDa, and is involved in maintaining the structure, transparency, and refractive index of the eye lens. Current disease research has linked defects in CRYBA4 to several types of cataracts, including lamellar 2 cataracts, zonular cataract, congenital cataracts, and microphthalmia cataract. Researchers are also studying the relation between the protein and the disorders choroididits and neurofibromatosis. CRYBA4 is included in several biological processes, including visual perception and camera-type eye development, through which it interacts with CRYBB2 and CRYBB3.

Alternate Names

Beta-A4 crystallin, beta-crystallin A4, crystallin, beta A4, crystallin, beta polypeptide A4, eye lens structural protein, MCOPCT4

Gene Symbol

CRYBA4

Additional CRYBA4 Products

Product Documents for CRYBA4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CRYBA4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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