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CRYZ Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16017

Novus Biologicals, part of Bio-Techne
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NBP2-16017

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Predicted:

Rhesus Macaque (96%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

IF/IHC, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human CRYZ. The exact sequence is proprietary.

Reactivity Notes

Rat (81%), Dog (87%), Pig (80%), Bovine (87%), Guinea pig (85%).

Localization

Cytoplasm;

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

35 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CRYZ Antibody

Western Blot: CRYZ Antibody [NBP2-16017]

Western Blot: CRYZ Antibody [NBP2-16017]

Western Blot: CRYZ Antibody [NBP2-16017] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 10% SDS PAGE gel, diluted at 1:500.
Immunocytochemistry/ Immunofluorescence: CRYZ Antibody [NBP2-16017]

Immunocytochemistry/ Immunofluorescence: CRYZ Antibody [NBP2-16017]

Immunocytochemistry/Immunofluorescence: CRYZ Antibody [NBP2-16017] - HepG2 cells were fixed in ice-cold MeOH for 5 min. Green: zeta Crystallin protein stained by zeta Crystallin antibody [N1C1] diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 um.
Immunohistochemistry-Paraffin: CRYZ Antibody [NBP2-16017]

Immunohistochemistry-Paraffin: CRYZ Antibody [NBP2-16017]

Immunohistochemistry-Paraffin: CRYZ Antibody [NBP2-16017] - Human hepatoma, using zeta Crystallin antibody at 1:500 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.

Applications for CRYZ Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CRYZ

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist. [provided by RefSeq]

Alternate Names

crystallin, zeta (quinone reductase), DKFZp779E0834, EC 1.6.5.5, FLJ41475, NADPH:quinone reductase, quinone oxidoreductase, zeta-crystallin

Gene Symbol

CRYZ

UniProt

Additional CRYZ Products

Product Documents for CRYZ Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CRYZ Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.