Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunoprecipitation, Western Blot (Negative)

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all CSB/ERCC6 Antibodies »

Product Summary for CSB Antibody

Immunogen

The immunogen recognized by this antibody maps to a region between residue 1161 and 1211 of human Cockayne syndrome protein B (excision repair cross-complementing rodent repair deficiency, complementation group 6) using the numbering given in entry NP_000115.1 (GeneID 2074).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CSB Antibody

Immunoprecipitation: CSB Antibody [NB100-61070]

Immunoprecipitation: CSB Antibody [NB100-61070]

Immunoprecipitation: CSB Antibody [NB100-61070] - Detection of Human ERCC6 on HeLa whole cell lysate using NB100-61070. ERCC6 was also immunoprecipitated by another rabbit anti-ERCC6 antibody NB100-61068 and NB100-61069.

Applications for CSB Antibody

Application
Recommended Usage

Immunoprecipitation

2 to 5 ug/mg lysate
Application Notes
It is not recommended for Western Blot.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: CSB/ERCC6

ERCC6, also known as Cockayne syndrome B protein, is involved in DNA repair in response to UV exposure. ERCC6 has been reported to display ATPase and helicase activity and functions as a transcriptional regulator. Mutations in ERCC6 are the cause of Cockayne syndrome type B (CSB), cerebro-oculo-facio-skeletal syndrome type 1 (COFS1), De Sanctis-Cacchione syndrome (DCS), age-related macular degeneration type 5 (ARMD5), and UV-sensitive syndrome (UVS).

Long Name

Cockayne Syndrome Protein, Type B

Alternate Names

ERCC6

Entrez Gene IDs

2074 (Human)

Gene Symbol

ERCC6

UniProt

NP_000115.1 (Human)

Additional CSB/ERCC6 Products

Product Documents for CSB Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CSB Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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