CSE1L/CAS/Exportin-2 Antibody (2B7)

Novus Biologicals, part of Bio-Techne | Catalog # H00001434-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human, Rat

Cited:

Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 2B7

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CSE1L/CAS Antibodies »

Product Specifications

Immunogen

CSE1L (NP_001307, 872 a.a. ~ 971 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. LIGLFELPEDDTIPDEEHFIDIEDTPGYQTAFSQLAFAGKKEHDPVGQMVNNPKIHLAQSLHKLSTACPGRVPSMVSTSLNAEALQYLQGYLQAARVTLL

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 21866187).

Specificity

CSE1L - CSE1 chromosome segregation 1-like (yeast)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for CSE1L/CAS/Exportin-2 Antibody (2B7)

Western Blot: CSE1L/CAS/Exportin-2 Antibody (2B7) [H00001434-M01]

Western Blot: CSE1L/CAS/Exportin-2 Antibody (2B7) [H00001434-M01]

Western Blot: CSE1L/CAS/Exportin-2 Antibody (2B7) [H00001434-M01] - CSE1L monoclonal antibody (M01), clone 2B7 Analysis of CSE1L expression in Hela S3 NE.
Immunocytochemistry/ Immunofluorescence: CSE1L/CAS/Exportin-2 Antibody (2B7) [H00001434-M01]

Immunocytochemistry/ Immunofluorescence: CSE1L/CAS/Exportin-2 Antibody (2B7) [H00001434-M01]

Immunocytochemistry/Immunofluorescence: CSE1L/CAS/Exportin-2 Antibody (2B7) [H00001434-M01] - Analysis of monoclonal antibody to CSE1L on HeLa cell. Antibody concentration 25 ug/ml.

Applications for CSE1L/CAS/Exportin-2 Antibody (2B7)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IF and ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CSE1L/CAS

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.

Long Name

Chromosome segregation 1-like protein

Alternate Names

CAS, CSE1, XPO2

Entrez Gene IDs

1434 (Human)

Gene Symbol

CSE1L

OMIM

601342 (Human)

UniProt

NP_001307 (Human)

Additional CSE1L/CAS Products

Product Documents for CSE1L/CAS/Exportin-2 Antibody (2B7)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CSE1L/CAS/Exportin-2 Antibody (2B7)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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