CSE1L/CAS/Exportin-2 Antibody (5111)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-43609

Novus Biologicals, part of Bio-Techne
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NBP2-43609
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Key Product Details

Validated by

Knockout/Knockdown

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%), Porcine (100%), Rhesus Macaque (100%), Xenopus (97%), Zebrafish (95%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 5111

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CSE1L/CAS Antibodies »

Product Summary for CSE1L/CAS/Exportin-2 Antibody (5111)

Immunogen

Recombinant protein encompassing a sequence within the center region of human CSE1L/CAS/Exportin-2. The exact sequence is proprietary.

Reactivity Notes

Xenopus laevis (97%).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for CSE1L/CAS/Exportin-2 Antibody (5111)

Western Blot: CSE1L/CAS/Exportin-2 Antibody (5111) [NBP2-43609]

Western Blot: CSE1L/CAS/Exportin-2 Antibody (5111) [NBP2-43609]

Western Blot: CSE1L/CAS/Exportin-2 Antibody (5111) [NBP2-43609] - Non-transfected (-) and transfected (+) 293T whole cell extracts (15 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with CSE1L antibody [5111].
Immunocytochemistry/ Immunofluorescence: CSE1L/CAS/Exportin-2 Antibody (5111) [NBP2-43609]

Immunocytochemistry/ Immunofluorescence: CSE1L/CAS/Exportin-2 Antibody (5111) [NBP2-43609]

Immunocytochemistry/Immunofluorescence: CSE1L/CAS/Exportin-2 Antibody (5111) [NBP2-43609] - CSE1L Antibody (5111) detects CSE1L protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: CSE1L stained by CSE1L Antibody (5111) diluted at 1:500. Red: phalloidin, a cytoskeleton marker, diluted at 1:100. Scale bar= 10um.
Western Blot: CSE1L/CAS/Exportin-2 Antibody (5111) [NBP2-43609]

Western Blot: CSE1L/CAS/Exportin-2 Antibody (5111) [NBP2-43609]

Western Blot: CSE1L/CAS/Exportin-2 Antibody (5111) [NBP2-43609] - Analysis of A. 30 ug 293T whole cell lysate/extract B. 30 ug A431 whole cell lysate/extract C. 30 ug HeLa whole cell lysate/extract D. 30 ug HepG2 whole cell lysate/extract 7.5 % SDS-PAGE CSE1L antibody [5111] dilution: 1:1000
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Applications for CSE1L/CAS/Exportin-2 Antibody (5111)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CSE1L/CAS

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.

Long Name

Chromosome segregation 1-like protein

Alternate Names

CAS, CSE1, XPO2

Gene Symbol

CSE1L

Additional CSE1L/CAS Products

Product Documents for CSE1L/CAS/Exportin-2 Antibody (5111)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for CSE1L/CAS/Exportin-2 Antibody (5111)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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