CTDSP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-57578

Novus Biologicals, part of Bio-Techne
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NBP2-57578
NBP2-57578-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (95%), Rat (93%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CTDSP1 Antibodies »

Product Summary for CTDSP1 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: EALPAHSGAPLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CTDSP1 Antibody

Immunocytochemistry/ Immunofluorescence: CTDSP1 Antibody [NBP2-57578]

Immunocytochemistry/ Immunofluorescence: CTDSP1 Antibody [NBP2-57578]

Immunocytochemistry/Immunofluorescence: CTDSP1 Antibody [NBP2-57578] - Staining of human cell line Hep G2 shows localization to nucleoplasm.

Applications for CTDSP1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CTDSP1

Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in theC-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase IItranscription, possibly by controlling the transition from initiation/capping to processive transcript elongation.Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronalcells

Alternate Names

carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) smallphosphatase 1, NIF3, NLI-IF, NLIIFEC 3.1.3.16, NLI-interacting factor 3, SCP1Nuclear LIM interactor-interacting factor 3, Small CTD phosphatase 1, Small C-terminal domain phosphatase 1

Gene Symbol

CTDSP1

Additional CTDSP1 Products

Product Documents for CTDSP1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CTDSP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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