Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human, Mouse

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin

Cited:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all CX3CR1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a peptide corresponding to amino acids 2 to 21 of human CX3CR1. The sequence differs from those of mouse and rat CX3CR1 by four amino acids (NP_001328).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CX3CR1 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: CX3CR1 Antibody - BSA Free [NBP1-76949]

Immunocytochemistry/ Immunofluorescence: CX3CR1 Antibody - BSA Free [NBP1-76949]

Immunocytochemistry/Immunofluorescence: CX3CR1 Antibody [NBP1-76949] - Staining of Human Heart cells with CX3CR1.
Immunohistochemistry-Paraffin: CX3CR1 Antibody - BSA Free [NBP1-76949]

Immunohistochemistry-Paraffin: CX3CR1 Antibody - BSA Free [NBP1-76949]

Immunohistochemistry-Paraffin: CX3CR1 Antibody [NBP1-76949] - Human tonsil, pH9 antigen retrieval. Image from verified customer review.
Immunohistochemistry-Paraffin: CX3CR1 Antibody - BSA Free [NBP1-76949]

Immunohistochemistry-Paraffin: CX3CR1 Antibody - BSA Free [NBP1-76949]

Immunohistochemistry-Paraffin: CX3CR1 Antibody [NBP1-76949] - Human heart tissue using CX3CR1 antibody at 2 ug/ml.

Applications for CX3CR1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

10ug/mL. Use reported in scientific literature

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

reported in scientific literature (PMID 20683935)

Immunohistochemistry-Paraffin

2 ug/ml

Reviewed Applications

Read 1 review rated 3 using NBP1-76949 in the following applications:

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CX3CR1

CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, murine, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration and adhesion. CX3CR1 is expressed in a variety of human tissues and cell lines.

Long Name

CX3C Chemokine Receptor 1

Alternate Names

CMKbRL1, V28

Entrez Gene IDs

1524 (Human); 13051 (Mouse); 171056 (Rat)

Gene Symbol

CX3CR1

UniProt

P49238 (Human)

Additional CX3CR1 Products

Product Documents for CX3CR1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CX3CR1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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