Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Mouse, Rat

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Cited:

ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all CXCR3 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 19 amino acid peptide near the carboxy terminus of human CXCR3 . The immunogen is located within the last 50 amino acids of CXCR3. Amino Acid Squence: RGLQRQPSSSRRDSSWSET

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Goat (89%), Bovine (88%).

Specificity

At least two isoforms of CXCR3 are known to exist; this antibody will detect both isoforms.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

43 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CXCR3 Antibody - BSA Free

Western Blot: CXCR3 AntibodyBSA Free [NBP2-41250]

Western Blot: CXCR3 AntibodyBSA Free [NBP2-41250]

Western Blot: CXCR3 Antibody [NBP2-41250] - Analysis of CXCR3 in HepG2 lysate with CXCR3 antibody at (A) 1 and (B) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: CXCR3 Antibody - BSA Free [NBP2-41250]

Immunocytochemistry/ Immunofluorescence: CXCR3 Antibody - BSA Free [NBP2-41250]

Immunocytochemistry/Immunofluorescence: CXCR3 Antibody [NBP2-41250] - CXCR3 in HepG2 cells with CXCR3 antibody at 20 ug/mL.
Immunocytochemistry/ Immunofluorescence: CXCR3 Antibody - BSA Free [NBP2-41250]

Immunocytochemistry/ Immunofluorescence: CXCR3 Antibody - BSA Free [NBP2-41250]

Immunocytochemistry/Immunofluorescence: CXCR3 Antibody [NBP2-41250] - Immunocytochemistry of CXCR3 in HepG2 cells with CXCR3 antibody at 5 ug/mL.
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Applications for CXCR3 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

5 -20 ug/ml

Western Blot

1 - 2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CXCR3

CXCR3, a Chemokine Receptor, is highly similar to the interleukine 8B receptor and has been shown to mediate recruitment of T cells to sites of inflammation and retention of T-cells in the inflamed CNS. CXCR3 has been suggested to be the principal inflammatory chemokine receptor involved in intrathecal accumulation of T-cells in multiple sclerosis and diabetes. It is expressed on malignant B cells in chronic lymphoproliferative disorders (Jones et al., 2000). An alternatively spliced isoform, CXCR3B, has recently been identified (Lasagni et al. 2003). CXCR3 expression has been documented in the brain, lymphoid and other peripheral tissues, and in diseasess including atheroslerosis, Alzheimer's, multiple sclerosis, rheumatoid arthritis, lymphomas, asthma, neoplasms, leukemia, and inflammatory conditions of various organs.

Alternate Names

CD183, CXCR3, GPR9

Gene Symbol

CXCR3

Additional CXCR3 Products

Product Documents for CXCR3 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CXCR3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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