CXCR6 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS1102

Novus Biologicals, part of Bio-Techne
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NLS1102
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Monkey

Cited:

Human, Mouse

Predicted:

Chimpanzee (100%), Primate (100%). Backed by our 100% Guarantee.

Applications

Validated:

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all CXCR6 Antibodies »

Product Specifications

Immunogen

Synthetic 16 amino acid peptide from 2nd cytoplasmic domain of human CXCR6.

Epitope

2nd Cytoplasmic domain

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 23653207). Predicted cross-reactivity based on sequence identity: Gorilla (100%), Marmoset (100%), Canine (88%), Bovine (88%), Equine (88%), Porcine (88%), Bat (81%).

Specificity

Human CXCR6. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for CXCR6 Antibody - BSA Free

Immunohistochemistry-Paraffin: CXCR6 Antibody - BSA Free [NLS1102]

Immunohistochemistry-Paraffin: CXCR6 Antibody - BSA Free [NLS1102]

Immunohistochemistry-Paraffin: CXCR6 Antibody [NLS1102] - Anti-CXCR6 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: CXCR6 Antibody - BSA Free [NLS1102]

Immunohistochemistry-Paraffin: CXCR6 Antibody - BSA Free [NLS1102]

Immunohistochemistry-Paraffin: CXCR6 Antibody [NLS1102] - Analysis of anti-CXCR6 antibody with human lung, adenocarcinoma.
Immunohistochemistry-Paraffin: CXCR6 Antibody - BSA Free [NLS1102]

Immunohistochemistry-Paraffin: CXCR6 Antibody - BSA Free [NLS1102]

Immunohistochemistry-Paraffin: CXCR6 Antibody [NLS1102] - Analysis of anti-CXCR6 antibody with human ovary, carcinoma.
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Applications for CXCR6 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

5 - 10 ug/ml
Application Notes
Use in ICC/IF reported in scientific literature (PMID: 23653207). Use in FLOW reported in scientific literature (PMID: 24302539)..

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: CXCR6

Coreceptor usage of primary human immunodeficiency virus type 1 (HIV-1) isolates varies according to biological phenotype. The chemokine receptors CCR5 and CXCR4 are the major coreceptors that, together with CD4, govern HIV-1 entry into cells. Some HIV-1, HIV-2, and SIV isolates of different genetic subtypes and biological phenotypes use other chemokine receptors, such as CXCR6, a T-lymphocyte-expressed seven-transmembrane domain receptor that mediates fusion, entry, and trafficking of tumor-infiltrating lymphocytes. CXCR6 has been identified in human blood (T-lymphocytes, activated peripheral blood lymphocytes, monocyte-derived dendritic cells, primitive cord blood cells), placental trophoblasts, T-lymphocytes and dendritic cells in the skin, lymphoid tissues, and in fetal brain astrocytes. ESTs have been isolated from human normal placenta, liver/spleen, and pregnant uterus libraries, and human cancer kidney and uterus libraries.

Alternate Names

Bonzo, CD186, CXCR6, STRL33

Entrez Gene IDs

10663 (Human)

Gene Symbol

CXCR6

Additional CXCR6 Products

Product Documents for CXCR6 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CXCR6 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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